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Use the following pedigree for the next 3 questions Alport syndrome is a disease that has both aut ...
Use the following pedigree for the next 3 questions Alport syndrome is a disease that has both autosomal recessive and \( x \)-linked recessive genetic types; patients with autosomal recessive Alport syndrome (ARAS) have recessive alleles of the COL4A3 gene located on chromosome 2; patients with \( x \)-linked recessive Alport syndrome (XLAS) have a recessive alleles(s) of the COL4A5 gene located on the \( X \) chromosome. The family shown in the pedigree is affected with Alport syndrome. Individuals 4 (Helen) and 7 (Sam), who are considering having another child, seek genetic counseling.
(2 points) The genetic counselor first seeks to determine what she can determine from the pedigree alone. Based on analysis of the entire pedigree, she concludes that... The left side of the family (individuals 1-4) have ARAS and the right side (individuals 5-8) have XLAS The left side of the family (individuals 1-4) have XLAS and the right side (individuals 5-8) have ARAS Both sides of the family must have ARAS Both sides of the family must have XLAS
Use the following pedigree for the next 3 questions Alport syndrome is a disease that has both autosomal recessive and \( x \)-linked recessive genetic types; patients with autosomal recessive Alport syndrome (ARAS) have recessive alleles of the COL4A3 gene located on chromosome 2; patients with \( x \)-linked recessive Alport syndrome (XLAS have a recessive alleles(s) of the COL4A5 gene located on the \( X \) chromosome. The family shown in the pedigree is affected with Alport syndrome. Individuals 4 (Helen) and 7 (Sam), who are considering having another child, seek genetic counseling. (2 points) What is the probability that Sam's sister (\#8) is a carrier of Alport Syndrome?
The family shown in the pedigree is affected with Alport syndrome. Individuals 4 (Helen) and 7 (Sam), who are considering having another child, seek genetic counseling. (2 points) What is the probability that Sam's sister (\#8) is a carrier of Alport Syndrome? \begin{tabular}{l} \hline \( 100 \% \) \\ \hline \( 2 / 3(67 \%) \) \\ \hline \( 1 / 2(50 \%) \) \\ \hline \( 1 / 3(33 \%) \) \\ \hline \( 1 / 4(25 \%) \) \\ \hline \( 1 / 6(16.7 \%) \) \\ \hline \end{tabular} \( 0 \% \)
Use the following pedigree for the next 3 questions Alport syndrome is a disease that has both autosomal recessive and \( \mathrm{x} \)-linked recessive genetic types; patients with autosomal recessive Alport syndrome (ARAS) have recessive alleles of the COL4A3 gene located on chromosome 2; patients with \( x \)-linked recessive Alport syndrome (XLAS) have a recessive alleles(s) of the COL4A5 gene located on the \( X \) chromosome. The family shown in the pedigree is affected with Alport syndrome. Individuals 4 (Helen) and 7 (Sam), who are considering having another child, seek genetic counseling.
(2 points) If Helen (\#4) and Sam (\#7) have another son, what is the probability that this son will have Alport Syndrome? \begin{tabular}{l} \hline \( 100 \% \) \\ \hline \( 2 / 3(67 \%) \) \\ \hline \( 1 / 2(50 \%) \) \\ \hline \( 1 / 3(33 \%) \) \\ \hline \( 1 / 4(25 \%) \) \\ \hline \( 1 / 6(16.7 \%) \) \\ \hline \end{tabular} \( 0 \% \)