(Solved): The quantitative differences in biological activity between the two enantiomers of a compound are s ...

The quantitative differences in biological activity between the two enantiomers of a compound are sometimes quite large. For example, the D isomer of the drug isoproterenol, used to treat mild asthma, is 50 to 80 times more effective as a bronchodilator than the Lisomer. Identify whether each of the indicated atoms in isoproterenol is a chiral center or achiral. Why do the two enantiomers have such radically different bioactivity? Isoproterenol binds to an achiral receptor. The isoproterenol receptor is a chiral molecule. L-isoproterenol inactivates receptor signaling. D-isoproterenol has fewer side effects than L-isoproterenol.