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(Solved): The following pedigree shows the inheritance of a completely penetrant, dominant trait called amel ...



The following pedigree shows the inheritance of a completely penetrant, dominant trait called amelogenesis imperfecta that af

The following pedigree shows the inheritance of a completely penetrant, dominant trait called amelogenesis imperfecta that affects the structure and integrity of the teeth. DNA analysis of blood obtained from the affected individuals III-1 and III-2 shows the presence of the same disease-causing mutation in one of the two copies of an autosomal gene called ENAM that is not seen from the blood of any of the parents in generation II. Where did the mutation that causes this trait arise (somatic cell or germline) and in which parent?


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Finding the source of the mutation in the pedigree and attempting to determine if it is a somatic or germline mutation are the objectives of this ques
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