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(Solved): The family tree below shows the inheritance of Duchenne muscular dystrophy in a family. This diseas ...
The family tree below shows the inheritance of Duchenne muscular dystrophy in a family. This disease is caused by a recessive allele of an -linked gene. normal female normal male affected male (a) (i) Indicate below the possible genotypes of individuals 1 to 10 . Use for the normal gene and for the Duchenne gene and and for the sex chromosomes. 1. 4. 7. 7. 10 2. 5. 8. 3 6. 9. (ii) What would a genetic counsellor say to parents 6 and 7 when explaining what the probability would be of their next child suffering from Duchenne muscular dystrophy? (b)Name two other X-linked diseases of humans.
Expert Answer
1. Male with normal X chromosome. 2. Carrier female with one X chromosome carrying the recessive allele for Duchenne Muscular Dystrophy. 3. Carrier female. 4. Affected male, as one X chromosome from the carrier mother can cause disease. 5. Affected male. 6. Carrier female, as paternal X chromosome is normal and maternal X chromosome is carrying the recessive allele for the disease. 7. Male with normal X chromosome. 8. Carrier female. 9. Affected male. 10. Affected male.If ne X chromosome is carrying the recessive allele for Duchenne Muscular Dystrophy, male will be affected & female will be carrier.