(Solved): Rapid depletion of ATP during strenuous muscular exertion causes the rate of glycolysis to increase ...

Rapid depletion of ATP during strenuous muscular exertion causes the rate of glycolysis to increase dramatically, producing higher cytosolic concentrations of pyruvate and NADH; lactate dehydrogenase converts these to lactate and NAD+ (lactate fermentation). The lactate produced during the sprint is transported to the liver, where it is acted upon by liver lactate dehydrogenase.

Assigned as ?? Q1C Why is the concentration of lactate not zero during the resting state? Responses Showing The ethanol consumed in alcoholic beverages is metabolized in the liver by alcohol dehydrogenase, which oxidizes ethanol to acetaldehyde using NAD+ as an oxidizing agent. The consumption of alcoholic beverages immediately after periods of strenuous activity results in a decrease in activity of liver lactate dehydrogenase, which leads to hypoglycemia (deficiency of glucose in the blood). Assigned as \( \cdots \) Q1D Based on the information provided, how does consuming ethanol decrease the activity of liver lactate dehydrogenase and why does this lead to hypoglycemia? Responses A congenital defect in the liver enzyme fructose 1,6-bisphosphatase results in abnormally high levels of lactate in the blood plasma, especially during strenuous exercise. Assigned as \( \ldots \) Q1E Explain why a deficiency in the liver enzyme fructose 1,6-bisphosphatase would result in increased blood lactate levels. Responses