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Procainamide is an antiarrhythmic used in the treatment of ventricular tachyarrhythmias. Determine ...
Procainamide is an antiarrhythmic used in the treatment of ventricular tachyarrhythmias. Determine the value of an intravenous loading dose of procainamide hydrochloride \( (S=0.87) \) that would achieve immediate plasma concentrations of \( 6 \mathrm{mg} / \mathrm{L} \) in a \( 70-\mathrm{kg} \) man. Procainamide's \( V d \) is \( 2 \mathrm{~L} / \mathrm{kg} \).