(Solved): During translation, translocation of the ribosome along the mRNA is facilitated by elongation facto ...

During translation, translocation of the ribosome along the mRNA is facilitated by elongation factor $C$ (EF-G). What does EF-G have in common with release factors? Both catalyze peptide bond formation between the nascent peptide chain and the incoming activated amino acid. They both use ATP to drive their respective function in translocation and in releasing the nascent polypeptide chain. Both bind aminoacyl-tRNAs, with RF binding the tRNAs that recognize stop codons. Both can bind at the ribiosme A site because they mimic the structure aminoacyl-tRNA bound to another of elongation factor (EF-Tu).