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(Solved): DNMT1 is the maintenance methylation enzyme; it maintains DNA methylation after DNA has replicated ...
DNMT1 is the maintenance methylation enzyme; it maintains DNA methylation after DNA has replicated. DNMT1 can also be involved in the recruitment of HDACs. In your research, you identify a mutation in DNMT1 that results in a change in the DNMT1 protein, specifically, it changes amino acid 501 (i.e., the 501 st amino acid in the primary sequence) from a tyrosine to a cysteine. This leads to early onset loss of sensation, resulting in painless injuries. Would you describe this as an epigenetic disorder and/or a genetic disorder? Explain your answer
DNMT1 is the maintenance methylation enzyme; it maintains DNA methylation after DNA has replicated. DNMT1 can also be involved in the recruitment of HDACs. In your research, you identify a mutation in DNMT1 that results in a change in the DNMT1 protein, specifically, it changes amino acid 501 (i.e., the 501 st amino acid in the primary sequence) from a tyrosine to a cysteine. This leads to early onset loss of sensation, resulting in painless injuries. Would you describe this as an epigenetic disorder and/or a genetic disorder? Explain your answer