Anatomy and Physiology A. What is the Lower Esophageal Sphincter (LES)? Where is it and what is its main function? What is the disease process when the LES is compromised? Pathophysiolgy A. Define GERD B. Define PUD 1. How can PUD create an obstruction or a perforation? C. Define Ca of the Stomach D. What is H. pylori and state how it affects the

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Anatomy and Physiology A. What is the Lower Esophageal Sphincter (LES)? Where is it and what is its main function? What is the disease process when the LES is compromised? Pathophysiolgy A. Define GERD B. Define PUD 1. How can PUD create an obstruction or a perforation? C. Define Ca of the Stomach D. What is H. pylori and state how it affects the GI tract? E. How does smoking cigarettes affect the GI svstem?

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