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(Solved): A binding curve for the binding of the amino acid tryptophan to the protein called TxtE is shown bel ...
A binding curve for the binding of the amino acid tryptophan to the protein called TxtE is shown below. Estimate the association equilibrium constant (Ka; in units of M-1) for Trp binding to TxtE.
Expert Answer
STEP 1 The binding of ligand 'L' to a protein 'P' to form Protein-Ligand complex 'PL' is represented below. P + L ?Ka PL Here 'Ka ' is the association equilibrium constant and has the unit Concentration-1 Ka =[PL][P][L] Generally ligand protein bindi