A 12-month-old male patient had a severe joint bleed as he began crawling. Laboratory results indicated an APTT of 120sec and a factor VIII assay of

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A 12-month-old male patient had a severe joint bleed as he began crawling. Laboratory results indicated an APTT of

>120sec

and a factor VIII assay of

<1(U)/(d)L

. What are three possible diagnoses for a patient with these values? What clinical and laboratory means are available to distinguish the three possibilities?

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