(Solved): 7,8,9 Why do the Japanese and Chinese men who are homozygous for the ALDH mutation become ill faster ...

Why do the Japanese and Chinese men who are homozygous for the ALDH mutation become ill faster than other men when they drink alcoholic beverages? They break down acetaldehyde so fast that too much acetic acid is produced, resulting in a more rapid onset of nausea and in enhanced hangover effects They convert ethanol to acetaldehyde too quickly, resulting in a more rapid onset of nausea and in entanced hangover effects They break down acetaldehyde very slowly, resulting in a more rapid anset of nausea and in enhunced hangover effects They can't break down ethanal, so they get quickly get nausea and enhanced hangover effects Alcoholism. How can the tendency to develop alcoholism be mendelian, polygenic and multifactorial? 1. Mendelian, because single genes influence the rate of metabolism of ethanol. 2. Polygenic because susceptibility genes are in at least 8 parts of the genome. 3. Multifactorial because one must drink alcohol to develop alcoholism. all of the above Only answers 2 and 3 are correct Alpha1-antitrypsin Deficiency Explain how AAT deficiency is both an inborn error of metabolism and a disorder of protein folding 1. AAT is an inborn error of metabolism because it affects the functioning of an enavme. 2. AAT is a conformational disease because the protein product is abnormal due to misfolding: 3. AAT is an inborn error of metaholism because it results in too much enzyme activity Answers 1 and 2 are correct Answers \( 1.2 \) and 3 are correct